I am an AI/ML Research Scientist at Bioscope AI, where I build a precision longevity platform integrating multi-omics data with neuroimaging. I recently graduated with a Ph.D. in Computer Science from Vanderbilt University, advised by Dr. Bennett A. Landman in the MASI Lab.

For my dissertation, I developed physics-informed neural networks to correct scanner-induced errors of 10–30% in quantitative brain imaging. I've contributed to two landmark studies: the first normative white matter brain charts (Nature, 2026) and the largest white matter asymmetry study to date (Human Brain Mapping, 2026). During my Ph.D., I also interned at the U.S. Food and Drug Administration (FDA), where I developed BEHYPE, a framework for detecting bias in AI-based medical devices.

A common thread across my work is translating AI research into clinical practice. I've developed, standardized, and optimized medical image analysis pipelines for reliable use in radiology workflows. My expertise spans deep learning, regulatory AI, image harmonization, and biomedical informatics.

Praitayini Kanakaraj
Research Interests

Physics-Informed Deep Learning · Diffusion MRI · Bias Field Correction · Gradient Nonlinearity Correction · AI Fairness & Trustworthiness · Medical Device Regulation · Clinical AI Infrastructure · LLMs in Healthcare · Neuroimaging · Brain Age Estimation · Multi-Omics Data Fusion


[2026] Our normative white matter brain charts paper is published in Nature, analyzing data from 42 cohorts worldwide.
[2026] White matter asymmetry study published in Human Brain Mapping (co-first author, 26,000+ scans) — the largest study of its kind.
[2026] Two preprints on LLM reasoning: "Beyond Consensus" and "When and How Long?" now on arXiv.
[Nov 2025] Joined Bioscope AI as AI/ML Research Scientist, building a precision longevity platform integrating neuroimaging, genomics, microbiome, wearables, and EHR data.
[Aug 2025] Successfully defended my Ph.D. dissertation at Vanderbilt University!
[2025] Provisional US patent filed for gradient-nonlinearity estimation and correction in diffusion MRI.
[2025] BEHYPE paper accepted at SPIE Medical Imaging 2025.
[Aug 2024] Invited talk at FDA Scientific Research Day: "Diverging Representations in AI Models for Improved Transparency."
[Jun 2024] Started research internship at U.S. FDA, Center for Devices and Radiological Health (CDRH).
[2024] DeepN4 paper published in Neuroinformatics. Contributed as open-source module to the DIPY library.

573+ Citations
58 Publications
12 h-index
13 i10-index

First Author

HIPAA clinical AI platform architecture

Workflow Integration of Research AI Tools into a Hospital Radiology Rapid Prototyping Environment

P. Kanakaraj, B.A. Landman et al.

Journal of Digital Imaging, 2022 · 17 citations

HIPAA-compliant platform · 6 AI tools across 7 departments

BEHYPE framework figure

BEHYPE: Bias Evaluation Using Hyperdimensional Computing for AI-Based Medical Devices

P. Kanakaraj, R.K. Samala, N. Petrick et al.

SPIE Medical Imaging, 2025

Developed at U.S. FDA CDRH

Gradient nonlinearity clinical study figure

Is Correction for Gradient Nonlinearity Necessary in a Brain Diffusion Tensor MRI Clinical Study?

P. Kanakaraj, T. Yao, Z. Li, N.R. Newlin et al.

PLoS ONE, 2026

DETERMINATOR framework overview

DETERMINATOR: Determinant Gradient Field Estimation for Accurate b-Value Correction in Diffusion MRI

P. Kanakaraj, L. Zuo, G. Rudravaram, T. Yao et al.

SPIE Medical Imaging, 2026

Gradient nonlinearity with noise impact figure

Mapping the Impact of Nonlinear Gradient Fields with Noise on Diffusion MRI

P. Kanakaraj, B.A. Landman et al.

SPIE Medical Imaging, 2023 · 6 citations

Efficient signal reconstruction figure

Efficient Approximate Signal Reconstruction for Correction of Gradient Nonlinearities in Diffusion-Weighted Imaging

P. Kanakaraj, B.A. Landman et al.

ISMRM, 2023 · 2 citations

XNAT BIDS export figure

Integrating the BIDS Neuroimaging Data Format and Workflow Optimization for Large-Scale Medical Image Analysis

S. Bao*, P. Kanakaraj* et al.  (*equal contribution)

Journal of Digital Imaging, 2022 · 8 citations

Replicated at Brown, Oxford, and UCL

Selected Contributions

Scalable neuroimaging infrastructure figure

Scalable, Reproducible, and Cost-Effective Processing of Large-Scale Medical Imaging Datasets

M.E. Kim, P. Kanakaraj et al.

PLoS ONE, 2025 · 28 citations

Beyond Consensus conceptual figure

Beyond Consensus: Trace-Level Synthesis in Mixture of Agents

S. Fadnavis, P. Kanakaraj et al.

arXiv, 2026

When and How Long readout-mediator figure

When and How Long? The Readout-Mediator Angle in Temporal Reasoning

S. Fadnavis, P. Kanakaraj et al.

arXiv, 2026

10 first-author papers · 47 total publications · 573+ citations Full list on Google Scholar →

AI/ML Research Scientist 2025 – Present

Bioscope AI

  • Precision longevity platform — genomics, microbiome, imaging, wearables, EHR
  • Neuroimaging module: 95+ structure segmentation, brain-age, 7 disease selectors
  • LLM clinical interpretation; SaMD regulatory clearance
Doctoral AI Researcher 2021 – 2025

Vanderbilt University — MASI Lab

  • Physics-informed deep learning for scanner bias correction
  • DeepN4: open-source contribution to DIPY
  • US patent for gradient-nonlinearity correction in dMRI
  • Mentored 4+ junior PhD and Masters students
AI/ML Research Intern 2024

U.S. Food & Drug Administration — CDRH/OSEL

  • BEHYPE framework for bias detection in breast imaging AI
  • Regulatory-science review on LLMs in clinical workflows
  • Invited talk at FDA Scientific Research Day
Staff Engineer, AI & Medical Imaging 2019 – 2021

Vanderbilt University

  • HIPAA-compliant AI platform across 7 departments
  • XNAT: 379+ projects, 48,556+ subjects, 480,000+ scans
  • BIDS tooling replicated at Brown, Oxford, and UCL
Senior Research Aide 2018 – 2019

Brookhaven National Laboratory

  • Computational modeling of lipid metabolism with CUDA
Graduate Research Assistant 2017 – 2019

Stony Brook University

  • 3D organ segmentation for radiation therapy (IEEE ISBI, 2020)
Education
Ph.D., Computer Science 2021 – 2025 Vanderbilt University
Advisor: Dr. Bennett A. Landman
Focus: Medical Image Processing
M.S., Biomedical Informatics 2017 – 2019 Stony Brook University
Advisor: Dr. Fusheng Wang
B.E., Biomedical Engineering 2013 – 2017 PSG College of Technology, India
Study Abroad: Colorado State; Flinders University, Australia

Invited Talks Peer Reviewer
NeuroImage Human Brain Mapping IEEE Trans. Signal Processing Scientific Reports Magnetic Resonance Imaging Digital Health J. Neurological Sciences SPIE Medical Imaging QIMS
Leadership

Programming & ML

Python PyTorch TensorFlow scikit-learn CUDA ONNX MATLAB C++ R SQL Bash

Medical Imaging

Structural MRI Diffusion MRI fMRI CT PET DIPY ANTs FreeSurfer FSL 3D Slicer MRtrix3 ITK NiBabel VTK SPM

Deep Learning

3D CNNs U-Net ResNets Transformers GANs VAE Diffusion Models LLMs Physics-Informed NNs Spherical CNNs

Infrastructure

Docker Singularity AWS GCP Git GitHub Actions HPC (SLURM/PBS) DICOM BIDS XNAT REST APIs HIPAA Compliance FDA Regulatory Science

Praitayini Kanakaraj

I grew up in Coimbatore, a city in southern India known for its engineering colleges and its proximity to the Western Ghats. From there, I've followed curiosity across three continents — studying in Australia on a full scholarship, researching at Brookhaven National Laboratory, and completing my Ph.D. at Vanderbilt in Nashville.

When I'm not debugging a neural network or reading a paper, you'll find me training for a marathon, on a yoga mat, or exploring a new city with a good hot chocolate in hand. I believe deeply that the curiosity which drives good science is the same curiosity that makes life interesting — and I try to bring that energy to everything I do.